HDAC9 and atherosclerosis: Most studies which found the high expression of HDAC9, highlight its role in the onset and progression of atherosclerosis, large vessel atherosclerotic stroke, increased risk of stroke and heart attack, etc. Therefore, there is also a growing body of research highlighting the importance of using selective and non-selective HDAC9 inhibitors in the treatment and prevention of atherosclerosis, heart attack, and stroke.