EIF2AK3 and metabolic dysfunction-associated steatotic liver disease: After the recovery of SERCA activity (restoration of Ca2+ homeostasis), the levels of the ERS-related markers GRP78, SREBP, p-PERK, p-eIF2α, and CHOP are reduced, inhibiting the progression of NAFLD in L02 and BEL-7402 hepatoma cells [99, 100].