It was also found that diseases such as arthritis, anemia and thyroid disorders are more common in patients with RLS [9], in study by Neyal et al., was reported that a family history of restless legs syndrome and increased gestational age increases the risk of RLS, It was also reported that blood urea nitrogen levels, high transferrin levels, and low levels of ferritin, increase the risk of restless legs syndrome [10]. The gene discussed is TF; the disease is anemia (phenotype).