CCND1 and breast cancer: To brief up using a head-head comparison, Patascil et al. [64] showed, in consistence with our used range of concentrations, that gamma-T3 was able to inhibit the cell proliferation in a dose- and time--dependent manner of both breast cancer cell lines involved in our study, then they demonstrate that a 40 μM of gamma-T3 was able to induce a modest G1-phase arrest associated with cyclin D1/D3 and CDK4 down-regulation, upon 24 h treatment in the MCF7 cells.