Multivariate analysis for diabetes remission at one year after BS shows that remission was associated with: age at the time of BS (OR 0.97, (0.96–0.99), p = 0.006), diabetes duration (OR 0.89, (0.86–0.92), p < 0.0001), presurgical BMI (OR 0.97, (0.94–0.99), p = 0.004), baseline HbA1c (OR 0.72, (0.65–0.79), p < 0.0001), insulin treatment (OR 0.23, (0.12–0.42), p < 0.0001) and weight loss 1 year after BS (OR 1.05, (1.03–1.07), p < 0.0001). This evidence concerns the gene INS and diabetes mellitus.