Reportedly, DPT interacts and increases TGF-β signalling [16] and, in this sense, we observed increased levels of TGFB1 mRNA in VAT from obese patients with T2D as well as a positive association of gene expression levels of DPT and TGFB1. TGF-β is a proangiogenic cytokine considered a master regulator of fibrosis in AT [34,35]. Here, TGFB1 is linked to type 2 diabetes mellitus.