HIF1A and cancer: A high glycolytic flux due to an overexpression of glycolytic enzymes regulated by HIF1α, changes in mitochondrial metabolism like a high flux in glutamine oxidation, and optimal capacity of ATP production through the respiratory chain, regulated by p53 and c-Myc [12,13,14], are metabolic pathways that contribute as a strategy for cancer cells to obtain the high amount of energy and de novo molecules needed for anabolic pathways [11].