These miRNAs are connected with proliferation, apoptosis, and cardiac injury [25] as well as transforming growth factor-β1 (TGF-β1) and glial cell line-derived neurotrophic factor (GDNF) regulation during glaucoma, asthma and obesity [26,27,28,29]. Here, TGFB1 is linked to obesity due to melanocortin 4 receptor deficiency.