Similarly, our results strongly suggested that FAM46C expression could be of clinical value as a prognostic indicator of several cancer types, such as BLCA, CSCC, HNSC, KIRC, LUAD, OC, PDAD, SARC or UCEC, and may as an independent prognostic factor play important role in prostate cancer. This evidence concerns the gene TENT5C and Familial prostate cancer.