Sub-eosinophils also correlated strongly with peak values during infection of several sputum inflammatory mediators and antimicrobial peptides including CXCL8/IL-8 (r = 0.86, P < .0001, Fig 6, B), IL-1β (r = 0.83, P = .0002, Fig 6, C), TNF (r = 0.77, P = .0007, Fig 6, D), pentraxin-3 (r = 0.78, P = .0003, Fig 6, E), LL-37 (r = 0.6, P = .012, Fig 6, F), and neutrophil elastase (r = 0.55, P = .023, Fig 6, G). This evidence concerns the gene CXCL8 and infection.