MARC1 p.A165T also associated with protection in cohorts where cirrhosis was ascertained using ICD codes (OR 0.91, p = 1.9x10-10) as well as in cohorts where cirrhosis was ascertained using clinical evaluation (OR 0.88, p = 0.04, p interaction = 0.65, S4 Fig). This evidence concerns the gene MTARC1 and Cirrhosis.