Blocking CD47 presumably tips the balance in favor of phagocytosis and as predicted, disruption of the CD47‐SIRPα interaction with anti‐CD47 antibodies has been demonstrated to enable phagocytosis of AML, ALL, and solid tumor cancer cells by human macrophages in vitro.14, 15, 16. This evidence concerns the gene CD47 and acute myeloid leukemia.