Correa et al. [48] found that lower IGFBP-3 levels were associated with worse outcomes in patients with cirrhosis: the low IGFBP-3 group had lower survival rates than high IGFBP-3 group in outpatients followed up for a median of 20 months (72.1% vs. 88.6%) and in hospitalized patients at 90-day transplant-free survival (56.1% vs. 80.4%). This evidence concerns the gene IGFBP3 and Cirrhosis.