Another retrospectively observational study enrolled 202 LC patients with sepsis and 87 of them with repeated CRP measurements at day 4 and/or 5; the results showed that the ratio of the follow-up CRP level to the initial CRP level might be a useful prognostic factor to predict the mortality of LC patients (OR: 19.12), but not initial CRP level [14]. Here, CRP is linked to laryngotracheoesophageal cleft.