Gungor et al. [33] reported that plasma NGAL (pNGAL) had potential ability to predict the outcome of liver cirrhosis in patients with hepatorenal syndrome (HRS): the patients with pNGAL>289.6 μg/L had a shorter survival time during 6-month follow-up, with AUROC 0.819 higher than CTP score (0.795), MELD-Na score (0.807), urine NGAL (0.686), and sensitivity 83.7% and specificity 72.2% in predicting mortality. This evidence concerns the gene LCN2 and hepatorenal syndrome.