NFKB1 and lip and oral cavity carcinoma: As the abnormal actuation and over-expression of the pro-inflammatory transcription agent, NF-κB contributes importantly to the regulation of different cellular procedures such as apoptosis, cell differentiation, signal transduction paths, and transformation, particularly over the development and metastasis process of multiple cancers such as oral cancer, unpaving the contribution of NF-κB proteins is of high importance [104].