CREBRF and acute myeloid leukemia: Then we used anti-miR-338-3p transfection to inhibit the expression of miR-338-3p in KG-1 and HL-60 cells (Fig. 5k), and miR-338-3p inhibitor brought about the up-regulation of CREBRF mRNA and protein expression in AML cells (Fig. 5l, m).