However, as is the case with qAF, data acquisition andanalysis may require a high-level expertise and computational proficiency thatcan impede its adoption as a routine method in the clinic or treatment trials.Nevertheless, the quantitation of autofluorescence holds promise as an effectiveoutcome measure in ABCA4-associated retinopathy, particularlyfor monitoring the effects of lipofuscin-targeted therapies. This evidence concerns the gene ABCA4 and retinal disorder.