We also obtained the elevated FGF23 levels of these seven patients before operation, ranging from 62.83 to 374.67 pg/mL comparing to the normal level of 10‐50 pg/mL.42 The pathological results indicated that tumours of TIO patients were all PMTs (Figure S1) and the locations of all the lesions were also been confirmed, consistently with our previous study.3 In this study, all the PMTs were around or inside the bone, but in different positions, including the medial right shoulder joint, left lateral femoral condyle, L5 left pedicle and left distal ulna and radius. The gene discussed is FGF23; the disease is neoplasm.