Furthermore, treatment of mutant K-Ras transgenic mice that developed PDAC with an anti-Myc drug showed an increase in cancer cell apoptosis, a reduction in cell proliferation, and a drastic attenuation of tumor growth, strongly suggesting anti-Myc drugs as potential chemotherapeutic agents for the treatment of PDAC (Stellas et al., 2014). This evidence concerns the gene KRAS and cancer.