CEACAM5 and neoplasm: Univariate analysis showed that Lauren classification (P = 0.032), nerve invasion (P = 0.017), vessel invasion (P = 0.006), differentiation degree (P = 0.009), tumor size (P < 0.001), CEA (P = 0.016), CA199 (P < 0.001), pT stage (P < 0.001), and LNM based on pathology (P < 0.001) were significantly association with prognosis (Table 6).