In colon homogenates and sera from control mice, C-X-C motif chemokine ligand 1 (CXCL1 and CXCL2 were barely detectable, while significant concentrations could be measured in homogenates and sera from WT CRC and TM CRC mice (Figure 4a–d). The gene discussed is CXCL1; the disease is colorectal carcinoma.