Similarly, miR-10b was shown to be associated with breast cancer survival and metastasis by upregulating epithelial–mesenchymal transition markers via downregulation of PTEN and activation of the Akt pathway in cancer stem cells [98], whereas miR-30b mediates proliferation and chemoresistance toward adriamycin of breast cancer by targeting PTEN [99]. This evidence concerns the gene AKT1 and breast carcinoma.