Although the initial genetic counseling may eventually need to include the possibility that heterozygote infants have a higher risk of CFTR-RD conditions [73,74,75,76,77], incidental detection of carrier status in false-positive infants does not yet seem actionable for the child because of the low absolute risks and thus the expectation that most CF heterozygotes will be healthy—at least until later in life. This evidence concerns the gene CFTR and cystic fibrosis.