PCLAF and nasopharyngeal carcinoma: To investigate the specific signaling pathway induced by KIAA0101 in NPC, LinkedOmics platform was employed to analyze co-expression genes with positive correlations (pearson test, r value > 0.2) with KIAA0101 in TCGA HNSC samples (Figure 5A, Supplementary Table 6), and Metascape enrichment result also showed that cell cycle (red dot) and DNA replication (green dot) may be induced by KIAA0101 in NPC (Figure 5B).