MAPT and early-onset autosomal dominant Alzheimer disease: Examples include amyotrophic lateral sclerosis induced by the fibration of FUS proteins,256 Alzheimer's Disease induced by the abnormal deposition of tau protein,257, 258 and Ewing's sarcoma induced by aberrant accumulation of proteins near the genome associated with tumorigenesis.259 The biomimetic construction of liquid organelle‐like materials in vitro provides a simplified alternative to understand the pathological phase transition of diseased organelles, thus shedding lights on the understanding of mechanism of neurodegenerative diseases and cancers.