TNF and Hepatic fibrosis: The anti‐inflammatory effect of PD has been confirmed in mice with nonalcoholic steatohepatitis,[qv: 23] and hepatic macrophages are known to play a central role in initiating and perpetuating inflammation which mediated the pathogenesis of hepatic fibrosis.[qv: 24] Thus, we explored whether PD‐MC could reduce the inflammatory reaction in LPS‐activated RAW cells and primary hepatic macrophages isolated from fibrotic mice by measuring the proinflammatory cytokines (IL‐1β, IL‐6, and TNF‐α).