To further illustrate the implication of TLR4 in the anti‐inflammatory effect of PD‐MC, we performed additional overexpression study in RAW cells and demonstrated that TLR4 DNA transfection significantly reversed the down‐regulation effects of PD‐MC on the TLR4/NF‐κB p65 signaling and inflammatory reaction after LPS stimulation (Figure S11B–D, Supporting Information). Here, TLR4 is linked to Parkinson disease.