In patients with glaucoma, TGF-β2 was found to stimulate Tenon's capsule fibroblast proliferation via suppression of miR-29b expression regulated by Nrf2 [117], which indicates that Nrf2 may protect cells against TGF-β and even fibrosis by upregulating miR-29b. This evidence concerns the gene NFE2L2 and glaucoma.