For example, AT-I has been shown to induce the G2/M phase of the cell cycle and cellular apoptosis in ovarian cancer cells by inhibiting the phosphatidylinositol 3-kinase/Akt/mammalian target of the rapamycin (PI3K/Akt/mTOR) pathway (Long et al., 2017). The gene discussed is MTOR; the disease is ovarian cancer.