CD47 and neoplasm: Specifically, SIGLEC-10 was found to be highly expressed by tumor-associated macrophages and mediated an antiphagocytic signal in the context of several tumors expressing its ligand CD24.74 Determining the specific engagement of CD47-dependent and CD24-dependent pathways in different tumor types will be relevant for the development of personalized immunotherapies based on the blockade of "do not eat me" signals.