These include depressive disorders,3 anxiety disorders,4 and diabetes-specific distress, such as fear of diabetes complications, hypoglycemia,5 insulin,6 disordered eating,7 the burden of living with T2D and stigma.8 Psychological treatments, such as cognitive–behavioral therapy (CBT) and counseling, including motivational interviewing, are offered with the aim of improving self-management. The gene discussed is INS; the disease is diabetes mellitus.