PTTG1 and Familial prostate cancer: Previous studies have revealed the oncogenic roles of PTTG1 in the tumorigenesis of many types of cancers including non-small cell lung cancer, hepatoma, prostate cancer, and breast cancer (Yoon et al. 2012; Liang et al. 2015; Li et al. 2013; Huang et al. 2014; Chen et al. 2006).