H19 and central nervous system cancer: Second, H19 expression is up-regulated in human lung cancers, gastric cancer, CRC, breast cancer, ovary cancer and glioma (Hu et al. 2018; Li et al. 2018; Yoruker et al. 2018; Dai et al. 2019; Si et al. 2019; Amit and Hochberg 2012) and associated with poor prognosis in these types of cancers.