H19 targets miR-138 to enhance SOX4 expression, leading to enhanced EMT and metastasis in breast cancers and glioma (Si et al. 2019) and sponges both miR-138 and miR-194-5-p to promote high mobility group A (HMGA1) expression, EMT and metastasis in CRC (Yang et al. 2017). The gene discussed is H19; the disease is central nervous system cancer.