CD79A and Decreased circulating IgG concentration: In contrast to studied PID patients, the great majority of whom had combined IgG and IgA or IgM deficiency, the majority of patients with secondary hypogammaglobulinemia had an isolated IgG deficiency, which comes in accordance with a previous study on hypogammaglobulinemia in patients with giant cell arteritis or polymyalgia rheumatic [26].