Specifically, the percentage of women and the prevalence of obesity, high blood pressure (BP), hyperglycaemia, low HDL cholesterol and abdominal obesity, and the prescription of antihypertensive agents, anti-cholesterol agents, insulin, oral hypoglycaemic agents, and aspirin or antiplatelet drugs increased with increasing MetS severity, whereas the education level decreased. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.