For example, the integrated analyses of T cells in HCC, NSCLC, and CRC revealed that although ZNF683+ CD8+ Trm cells were present in these 3 cancer types, their frequency was significantly higher in NSCLC than in HCC and CRC, suggesting potential function of these Trm cells in NSCLC immunity.60, 61. The gene discussed is CD8A; the disease is colorectal carcinoma.