MAGEA6 and cancer: To examine the effects of the cancer-specific variants in the proper cell lineage, we stably expressed the MAGEA6 variants in non-transformed human pancreatic ductal epithelial cells (HPDE-iKRAS) (Tsang et al., 2016) and two PDAC cell lines, BxPC-3 and MIA PaCa-2 using lentivirus (Figure 4A andFigure 4—figure supplement 1).