MAGEA1 and cancer: The MAGEA gene family is located on the X chromosome and consists of thirteen protein-encoding genes (MAGEA1 to A6, A8 to A12, A2B, and A9B) and one pseudogene, MAGEA7P. About 1000 unique non-silent MAGEA gene aberrations have been identified by ICGC (ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, 2020), The Cancer Genome Atlas (TCGA), and Catalogue of Somatic Mutations in Cancer (COSMIC) (Tate et al., 2019) pan-cancer analyses (Figure 1A).