There were no statistically significant differences in serum IL-6 level between pruritic and non-pruritic CTCL patients (VAS p = 0.71; NRS p = 0.84) No positive correlation was found between serum IL-6 levels and severity of pruritus in CTCL (VAS p = 0.68; NRS p = 0.58). Here, IL6 is linked to primary cutaneous T-cell non-Hodgkin lymphoma.