A notable example is the SNPs located in the SPTBN1 coding region, where the SNP-association signals are significant and consistent across GWAS and eQTL datasets with PSMR = 3.15E-19 for BMD and PSMR = 2.20E-04 for osteoporosis (Figure 4A). This evidence concerns the gene SPTBN1 and osteoporosis.