As ISLQ has been shown to increase the expression of Bax, decrease the expression of Bcl-2, and lead to caspase-dependent cell death in human carcinoma and hepatoma cells [37,38], we examined the involvement of Bax, Bcl-2, and caspases in ISLQ-induced cell death in SK-N-BE(2) cells. The gene discussed is BAX; the disease is hepatocellular carcinoma.