The Kaplan-Meier curve and log rank test analyses were shown in Fig. 5, higher mRNA expression of GBP2 (HR = 2.08, 95% CI: 0.99–4.37, P = 0.048) and GBP3 (HR = 2.09, 95% CI: 0.99–4.42, P = 0.049) were significantly associated with shorter relapse free survival (RFS) of HNSCC patients. Here, GBP3 is linked to head and neck squamous cell carcinoma.