TDG and neoplasm: Since a positive correlation between HOTAIRM1 and TDG expression levels was observed in tumor tissues (r = 0.34, p = 0.0024, Fig. 7g), we sought to determine whether the regulation of TDG expression was influenced by HOTAIRM1. The results of qRT-PCR and western blotting indicated that the overexpression of HOTAIRM1 increased the mRNA and protein levels of TDG (Fig. 7h–i).