Subgroup analyses on clinical features revealed that low HOTAIRM1 expression levels were significantly correlated with advanced stage (TIII and TIV; p = 0.0497; Fig. 1c, Supplementary Table 1) and lymph node metastasis (p < 0.01, Supplementary Table 1). Here, HOTAIRM1 is linked to metastatic malignant neoplasm in the lymph nodes.