TAGAP and Autoimmunity: The C7-Dnajb1hi–activated Tregs express early response inflammatory (Dnajb1 [Regateiro et al, 2012], Hspa1a [Wachstein et al, 2012; Collins et al, 2013], Tagap [Arshad et al, 2018], and interferonresponse–related) genes, some of which are associated with enhanced Treg function and autoimmunity (Fig S10A).