Recently, we showed that both Lin28A and LIN28B were significantly decreased and levels of let-7 miRNAs (let-7a, let-7b, let-7c, let-7d, let-7e, let-7f, let-7g, let-7i) were significantly increased in term human placentas from IUGR pregnancies compared to control pregnancies [18]. The gene discussed is LIN28B; the disease is fetal growth restriction.