GSTP1 and posterior cortical atrophy: Exposure of human PCa LNCaP cells to 1–10 μg/mL of Polyphenon E for 1 to 7 days provoked the downregulation of DNMT1 mRNA and protein expression, which caused a reversal in glutathione-S-transferase P1 (GSTP1) CpG island hypermethylation and restoration of GSTP1 expression [174].