These data fit well with our previous transcriptional microarray analysis of the lungs of double transgenic K-RasG12D/p53R172HΔg mice [84] from which ROS1 mRNA resulted significantly increased in K-RasG12D/p53R172HΔg double transgenic mice, as compared to wt mice, at the different time points analyzed (Figure S2), despite no correlation between ROS1 expression levels and tumor progression being observed. This evidence concerns the gene ROS1 and neoplasm.