DNAJB8 and hereditary clear cell renal cell carcinoma: It was reported in 2012 that DnaJB8 promotes CSC phenotype development in renal cell carcinoma: Being overexpressed, DnaJB8 increased the percentage of CSC-like SP cells and enhanced their tumorigenicity, whereas the attenuation of DnaJB8 diminished the amounts of SP cells whose tumorigenicity became impaired [128].