Haishengsu (HSS), a protein extract from the seashell Tegillarca granosa, promotes apoptosis in adriamycin-resistant leukemia cells inoculated in mice, by reducing expression of sorcin and ABCB1 [143] (other effects on other targets cannot be excluded, considering that this protein extract is poorly characterized from a molecular viewpoint). Here, ABCB1 is linked to leukemia.