SRI and leukemia: Sorcin overexpression increases ABCB1 expression, determining increased drug resistance to several drugs, while sorcin silencing decreases expression of ABCB1, increasing cell death, in gastric cancer cells, lung tumor cells, nasopharyngeal carcinoma, cervical carcinoma cells, and leukemias [24,32,34,52,57,60,66,68,69,74].