For instance, a gene expression microarray analysis of PLK1 knockdown in bladder cancer cells [50] revealed GO biological processes, such as cell cycle, focal adhesions, VEGF and NF-κB signaling pathways deregulated, similar to what we found in our transcriptomic analysis, hence underlying most of the pathways modulated by BORA are PLK1-dependent. The gene discussed is BORA; the disease is urinary bladder cancer.