HIV infection (OR = 6.80; 95% CI = 2.33–19.85; I2 = 0%) and SLC11A1 rs17235409 A allele (OR = 1.86; 95% CI = 1.25–2.77; I2 = 0%) are associated with increased prevalence of the disease. This evidence concerns the gene SLC11A1 and HIV infectious disease.