Shimosawa Shimosawa T T Salt, the renin-angiotensin-aldosterone system and resistant hypertension Salt, the renin-angiotensin-aldosterone system and resistant hypertension Hypertens Res Hypertens Res 2013 2013 36 36 8 8 657 657 660 660 23912973 23912973. This evidence concerns the gene REN and Hypertension resistant to conventional therapy.