TP53 and infection: The overexpression of hsa-miR-217 increased P53 (p<0.0001) and KAI1 protein level (p<0.0001) in PC-14/B cells compared with controls, and the infection of Lv-SIRT1 decreased the expression of P53 (p=0.006) and KAI1 proteins significantly (p=0.050 vs control; Figure 5B and C).